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Manchester City winger Riyad Mahrez and defender Aymeric Laporte have tested positive for Covid-19.
Algeria’s Mahrez, 29, and Frenchman Laporte, 24, will not train with their team-mates while they self-isolate in line with UK government and Premier League rules.
Manchester City say neither player was displaying symptoms of coronavirus.
Pep Guardiola’s side play Wolverhampton Wanderers in their first fixture of the new league season on 21 September.
